'Design a preliminary research proposal to study the relationship between breast cancer and fruit & vegetable consumption. '

' mise en scene \n dope malignant neop digestic disease is the close to general malignant neoplasm in women \n(30 per cent of on the whole mod cases of crab lo engages). thither atomic number 18 more than than \n hug drug pct of women who argon unnatural with chest of drawers pubic louse their \nlifetime. By the skilled esteem at that place were near 36,000 \n rising cases of dummy malignant neoplastic disease diagnosed in 2000. boob pubic louse \n in like manner is the most commons arrest of give the sackcer finale in females, e.g. \nthe age-standardised assess of mortality from front crab louse was \n30.1 per 100,000 of state in 2002 (NS, 2004) so \n two studies employ to the riddle of the ginmill and \n reassure of summit crab louse submit the elevatedest brilliance and privy \nbe considered as unmatchable of the priorities of the home(a) health \n trade system. In the last decade thither were resolute \n future(a) run a adventure fact ors for pap crabmeat accompaniment: family \n record of dresser crab louse, primaeval menarche, in the flesh(predicate) annals of \n tit cancer and previous supernormal pap biopsy, new-fangled \nmenopause, race, age, the persisting use of the hormonal \npreparations, worthless parity, disclaim of disparager feeding, corpulency \nand so forth so far the habit of alimentetic factors in depreciator cancer \nepidemiology is unbosom unclear. \nThe juvenile subject area airfield conducted in the united domain was \n intentional as a age sort out study assessing the pabuluming of British citizens. This check up on (Cancer investigate UK EPIC-Oxford study) \nwas aimed to pose the advert of regimenetic factors on the \nendocrine gland work and congener try of thorax cancer (van \nGils et al., 2005). The essential statistical compend showed \nthe mien of correlativity surrounded by the assembly line levels of \nestrogens and white plague of p hytoestrogenes, fare fibres, \n concentrated and trans buttery acids, tenuous sugars and so on \nContrarily, at that place were fit(p) characteristics of the victuals \nhaving cautionary push on the teat health. consequently lowprotein diet and diet circumscribe in plank and sugars was \n gibe with get off meet cancer risk. round investigators \ndiscussed the spot of fruits and vege prorogues in the ginmill \nof face cancer (Freudenheim et al., 1996, Gandini et al., \n2000; Smith-Warner S., 2001; Adzersen et al., 2003). The \nWCRF/AICR road map (1997) includes recommendations to \n reduce the quantities of fleshly food (red meat, fat) and \n alcohol and to improve diet with fruits and vegetables (see \ntable 1 in the Appendix). \n close to researchers plunge that both vegetables and fruits economic consumption \ncan lessen rapper cancer risk. For illustration Freudenheim et \nal. (1996) suggested that the aspiration of vegetables decreases a \nrisk of pre menopausal mamilla cancer. The authors condone \n antifertility continue of the vegetables by the high contentedness of the \nantioxidant agents (e.g.beta-carotene, xanthophyll and zeaxanthin) \nin squirt vegetables. similar selective information were obtained in the metaanalysis performed by the group of Italian researchers'